The mechanism of the biological synthesis of acetylcholine

As a result of our work on choline-esterase, the enzyme responsible for the destruction of acetylcholine, we were led, some 2 years ago, to commence an investigation which had as its objective the elucidation of the mechanism whereby acetylcholine is synthesized in the animal organism. This objective has not yet been achieved. In view, however, of the recent publication of Quastel et al. [1936] on the same theme, it appears to us desirable to publish the results which we have already obtained.