Why the study?
Does significant weight loss reverse maladaptive enlargement of the brachial artery in severely obese patients?
Population
244 severely obese patients (age 44 +/- 11 years, 80% female, body mass index (BMI) 46 +/- 9 kg/m2)
Comparison
Significant (>= 10%) weight reduction vs Baseline (pre-weight loss)
Design
Cohort
Follow-up
1 year
Authors
Loading...
May support reversal of maladaptive arterial remodeling after weight loss; leaves open need for outcome trials before clinical adoption.
Does significant weight loss reverse maladaptive enlargement of the brachial artery in severely obese patients?
Significant weight loss in severe obesity reverses maladaptive peripheral arterial remodeling, as evidenced by decreased brachial artery diameter.
Hamburg et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: