Assessment of left ventricular long axis contraction can detect early myocardial dysfunction in asymptomatic patients with severe aortic regurgitation
Why the study?
Does resting assessment of left ventricular long axis contraction detect subclinical myocardial dysfunction in asymptomatic patients with severe aortic regurgitation?
Population
21 asymptomatic patients with severe aortic regurgitation
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support resting long-axis velocity to detect subclinical dysfunction in asymptomatic severe AR; hypothesis-generating, requires prospective validation before practice change.
Structured PICO
Does resting assessment of left ventricular long axis contraction detect subclinical myocardial dysfunction in asymptomatic patients with severe aortic regurgitation?
P
Population
21 asymptomatic patients (NYHA functional class ≤ 2a) with severe aortic regurgitation (jet area/left ventricular outflow tract area > 40%)
I
Intervention
Assessment of left ventricular long axis contraction at rest using tissue Doppler and M mode echocardiography
O
Outcome
Left ventricular ejection fraction (LVEF) at baseline and peak exercise (Weber protocol), cardiopulmonary function, and left ventricular long axis function at rest (peak systolic velocity and excursion of the mitral annulus)surrogate
Resting tissue Doppler assessment of left ventricular long axis contraction can reliably identify subclinical myocardial dysfunction in asymptomatic patients with severe aortic regurgitation.
Cite This Study
Dragoş Vinereanu (2001) studied this question.