Why the study?
Does left ventricular hypertrophy reduce carotid wall shear stress in subjects with atherosclerosis risk factors?
Population
80 subjects with at least one risk factor for atherosclerosis
Comparison
Left ventricular hypertrophy based on left… vs No left ventricular hypertrophy (LVH-)
Design
Cross-sectional
Authors
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May link LVH to carotid atherosclerosis via hemodynamics; leaves open causality and clinical relevance in cross-sectional data.
Does left ventricular hypertrophy reduce carotid wall shear stress in subjects with atherosclerosis risk factors?
Low carotid wall shear stress is independently correlated with left ventricular mass index, suggesting a local hemodynamic mechanism linking left ventricular hypertrophy to carotid atherosclerosis development.
Jiang et al. (2000) studied this question.
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