Key result
Smoking cessation for 3 years did not significantly reduce the progression of major electrocardiographic abnormalities compared to continued smoking (5.9% vs 6.5%, OR 1.17).
Why the study?
Does smoking cessation reduce ECG abnormalities in smokers?
Cohort (n=532)
Double-blind
No
Does smoking cessation reduce ECG abnormalities in smokers?
Odds Ratio: 1.17 (95% CI 0.48–2.82)
Absolute Event Rate: 5.9% vs 6.5%
p-value: p=0.727
Major ECG abnormalities are independently associated with lifetime smoking burden, but 3 years of smoking cessation does not significantly reduce these abnormalities compared to continued smoking.
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Three-year smoking cessation was not associated with slower ECG abnormality progression; leaves open longer-term effects and need for randomized trials.
Gepner et al. (2013) conducted a cohort in Cigarette smoking (n=532). Smoking cessation vs. Continued smoking was evaluated on Progression of major ECG abnormalities at 3 years (OR 1.17, 95% CI 0.48-2.82, p=0.727). Smoking cessation for 3 years did not significantly reduce the progression of major electrocardiographic abnormalities compared to continued smoking (5.9% vs 6.5%, OR 1.17).
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