Key result
Smoking in healthy males is linked to ECG abnormalities and ~4 mmHg higher SBP.
Why the study?
Nicotine in cigarette smoke impairs cardiac electrical conduction, but the electrocardiographic profile differences between seemingly fit smokers and non-smokers warranted evaluation.
Does smoking alter ECG profiles in seemingly fit males?
Observational (n=148)
No
Does smoking alter ECG profiles in seemingly fit males?
Smoking is associated with ECG abnormalities and higher systolic blood pressure in seemingly healthy young men, potentially indicating early cardiovascular risk.
May flag early CV risk in young male smokers; hypothesis-generating and requires prospective validation before clinical adoption.
Background and Aim: The nicotine present in the cigarette smoke induces conduction block, acts as a cardiac A-type potassium channels blockers and increase the ventricular fibril formation which also changes the cardiac electric impulses usually assessed via electrocardiogram (ECG).The present study aims to evaluate and compare the ECG profile change in seemingly fit smokers and non-smokers.Materials and Methods: The present study was conducted in the Department of Medicine, for two years involved 148 patients evaluated for different parameters heart rate, the PR interval, QRS complex QTc (corrected QT interval) using a 12 lead ECG. P-value < 0> Results: All the patients were male and the mean age was comparable in non-smoking group (NS) vs smoking group (S) (29.26±5.90 vs. 30.42±6.19 years; p=0.244). Mean systolic (127.43 ± 7.29 (S) vs. 123.03 ± 6.96 (NS) mm Hg; p<0 p=0.003)> Conclusion: Smokers show abnormalities in the ECG profile that may eventually increase the risk of incidence of cardiovascular diseases.
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Kumar et al. (2022) conducted an observational in Healthy (n=148). Smoking vs. Non-smokers was evaluated on ECG profile changes (heart rate, PR interval, QRS complex, QTc). Healthy male smokers showed abnormalities in their ECG profile and higher mean systolic blood pressure (127.43 vs 123.03 mm Hg) compared to non-smokers.
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