Why the study?
What are the causative organisms and outcomes of medical versus surgical management in early and late prosthetic valve endocarditis?
What are the causative organisms and outcomes of medical versus surgical management in early and late prosthetic valve endocarditis?
Early prosthetic valve endocarditis carries high mortality with medical therapy and likely requires prompt surgical replacement, whereas late-onset disease can often be managed medically.
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Early PVE may warrant surgery while late-onset often responds to medical therapy; leaves open need for confirmatory prospective data.
Moore-Gillon et al. (1983) studied this question.
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