Why the study?
What are the common pathogens, timing of presentation, and causes of mortality in patients with prosthetic valve endocarditis?
Population
23 patients with 24 episodes of prosthetic valve endocarditis over a 10-year period.
Design
Case_series
Follow-up
Up to 7 years after surgery
Authors
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Negative cultures may delay treatment in prosthetic valve endocarditis; hypothesis-generating for early vs late pathogen patterns.
What are the common pathogens, timing of presentation, and causes of mortality in patients with prosthetic valve endocarditis?
Early prosthetic valve endocarditis is frequently caused by opportunistic pathogens, whereas late cases are typically due to Streptococcus viridans, with negative blood cultures often delaying life-saving treatment.
Petheram et al. (1977) studied this question.
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