Key result
New-onset atrial fibrillation was independently associated with a significantly increased risk of in-hospital death (adjusted OR 3.92) compared to no atrial fibrillation in patients with infective endocarditis.
Why the study?
Few large-sample studies have evaluated the incidence, risk factors, and prognostic value of new-onset AF in patients with infective endocarditis.
Does new-onset atrial fibrillation increase the risk of mortality in patients with infective endocarditis?
Population
1,063 IE patients
Comparison
New-onset AF vs no-AF or prior AF
Design
Observational cohort study
Follow-up
1-year
Authors
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New-onset AF warrants close monitoring in IE; leaves open whether rhythm interventions alter outcomes.
Observational (n=1,063)
No
Does new-onset atrial fibrillation increase the risk of mortality in patients with infective endocarditis?
Odds Ratio: 3.92 (95% CI 1.7–9.04)
Absolute Event Rate: 22.9% vs 6%
p-value: p=0.001
New-onset atrial fibrillation in patients with infective endocarditis is an independent predictor of short-term and in-hospital mortality.
Wei et al. (2019) conducted an observational in Infective endocarditis (n=1,063). New-onset atrial fibrillation vs. No atrial fibrillation was evaluated on In-hospital all-cause death (adjusted OR 3.92, 95% CI 1.70-9.04, p=0.001). New-onset atrial fibrillation was independently associated with a significantly increased risk of in-hospital death (adjusted OR 3.92) compared to no atrial fibrillation in patients with infective endocarditis.
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