Biatrial pacing improves atrial haemodynamics and atrioventricular timing compared with pacing from the right atrial appendage
Key result
Biatrial pacing improved left atrial contractility (P≤0.03) and yielded the shortest delay to peak a-wave (P≤0.001) compared with pacing from the right atrial appendage.
Why the study?
Does multisite or biatrial pacing improve atrial hemodynamics and atrioventricular timing compared with right atrial appendage pacing in patients with paroxysmal atrial fibrillation?
Population
24 patients undergoing radiofrequency ablation for paroxysmal atrial fibrillation
Comparison
Pacing from the high interatrial septum, distal… vs Pacing from the right atrial appendage and sinus…
Design
Other
Follow-up
acute (during procedure)
Authors
Discussion
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Member takes
Implication
May not yet change pacing site selection in paroxysmal AF; leaves open whether acute gains improve long-term outcomes.
Structured PICO
Does multisite or biatrial pacing improve atrial hemodynamics and atrioventricular timing compared with right atrial appendage pacing in patients with paroxysmal atrial fibrillation?
P
Population
24 patients undergoing radiofrequency ablation for paroxysmal atrial fibrillation.
I
Intervention
Pacing from the high interatrial septum (IAS), distal or proximal coronary sinus (CSD and CSP), and biatrial (BiA) pacing from the IAS + CSD
C
Comparator
Pacing from the right atrial appendage (RAA) and sinus rhythm
O
Outcome
Left atrial contractility (+dP/dT(max)) and timing of the a-wave (delay to peak a-wave, AV conduction)surrogate
Main Result
p-value: p=≤0.03
Biatrial pacing acutely improves left atrial contractility and atrioventricular synchrony compared to right atrial appendage pacing.
Cite This Study
Burri et al. (2011) studied paroxysmal atrial fibrillation (n=24). Biatrial pacing vs. Pacing from the right atrial appendage was evaluated on Left atrial contractility (+dP/dT(max)) (p=≤0.03). Biatrial pacing improved left atrial contractility (P≤0.03) and yielded the shortest delay to peak a-wave (P≤0.001) compared with pacing from the right atrial appendage.