Key result
Ambulatory blood pressure yielded lower cutoff values for hypertension stages compared to clinic blood pressure, with a mean systolic bias of -13.3 mm Hg (95% CI -14.3 to -12.2).
Why the study?
Does 24-hour ambulatory blood pressure monitoring provide corresponding stages of hypertension and prognostic value compared to clinic blood pressure in hypertensive patients?
Population
736 hypertensive patients
Comparison
24-hour ambulatory blood pressure (ABP) monitoring vs Clinic blood pressure (CBP) measurement
Design
Cohort
Authors
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ABP may require lower stage thresholds than clinic BP; extends calibration data while leaving prognostic validation open.
Observational (n=736)
Does 24-hour ambulatory blood pressure monitoring provide corresponding stages of hypertension and prognostic value compared to clinic blood pressure in hypertensive patients?
Mean Difference: -13.3 (95% CI -14.3–-12.2)
Absolute Event Rate: 135% vs 149%
p-value: p=>0.0001
Ambulatory blood pressure monitoring yields lower cutoff values for hypertension stages than clinic blood pressure, and these ABP stages are significantly associated with cardiovascular events, supporting its use for assessing disease severity and prognosis.
Bur et al. (2002) conducted an observational in Hypertension (n=736). Ambulatory blood pressure (ABP) vs. Clinic blood pressure (CBP) was evaluated on Mean bias between ambulatory and clinic systolic blood pressure (MD -13.3, 95% CI -14.3 to -12.2, p=>0.0001). Ambulatory blood pressure yielded lower cutoff values for hypertension stages compared to clinic blood pressure, with a mean systolic bias of -13.3 mm Hg (95% CI -14.3 to -12.2).
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