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;The materials and methods used to allow quantitative assessment of the vasoconstrictor response to steroids applied in formulated vehicles are described. Illustrations are given of the application of the assay to (1) an assessment of the effect of varying the base on the vasoconstrictor response to different concentrations of a specific steroid, (2) an assessment of the effect of varying one constituent of a specific base, and (3) a comparison of the vasoconstrictor activity of occluded and unoccluded bases.
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Christie et al. (1970) studied this question.
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