The severity of rotavirus infection appears to be related to the nature of the systemic and secretory antibody response, with severe disease associated with lower convalescent serum IgG and higher fecal secretory IgA.
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May link lower IgG/higher secretory IgA to severe rotavirus; hypothesis-generating, should not change practice without prospective data.
Riepenhoff-Talty et al. (1981) studied this question.
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