November 16, 2020Current Opinion in Nephrology & Hypertension
Novel approaches to management of hypertension
Key result
Recent guidelines and studies support initiating hypertension treatment with single-pill combination therapy and highlight renal denervation as a promising interventional therapy.
Why the study?
Only about one in seven of the roughly 1.4 billion people with hypertension worldwide has blood pressure successfully treated and adequately controlled.
Design
Review
Authors
Discussion
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Implication
May support initial combination therapy and renal denervation in hypertension; leaves open comparative effectiveness and long-term outcomes.
Structured PICO
P
Population
People with hypertension
I
Intervention
Combination therapy, single-pill combinations (SPC), and renal denervation (RDN)
Recent guidelines and trials support the use of initial combination therapy, single-pill combinations, and renal denervation for the management of hypertension.
Limitations
- Identifying patients who respond best to interventional treatment remains a challenge
Cite This Study
Bosch et al. (2020) conducted a review in Hypertension. New therapeutic approaches (combination therapy, single-pill combinations, renal denervation) was evaluated. Recent guidelines and studies support initiating hypertension treatment with single-pill combination therapy and highlight renal denervation as a promising interventional therapy.