Key result
Sedentary time and breaks did not moderate the relationship between vascular and cognitive function in older adults with preclinical cognitive impairment with and without CKD.
Why the study?
Older adults with and without CKD commonly experience cognitive impairment, vascular dysfunction, and sedentary behavior, but whether sedentary behavior influences the relationship between cognitive and vascular function in this population was unexplored.
Does sedentary behavior influence the relationship between cognitive and vascular function in older adults with preclinical cognitive impairment with and without CKD?
Cross-Sectional (n=48)
Does sedentary behavior influence the relationship between cognitive and vascular function in older adults with preclinical cognitive impairment with and without CKD?
Sedentary time and breaks do not significantly moderate the relationship between vascular and cognitive function in older adults with preclinical cognitive impairment.
Should not yet change practice; hypothesis-generating for longitudinal studies on sedentary behavior in preclinical impairment.
Cognitive impairment and vascular dysfunction are common in older adults with and without chronic kidney disease (CKD). Older adults with and without CKD are also sedentary - a behavior associated with cognitive and vascular function. The objective of this study was to explore whether sedentary behavior influenced the relationship between cognitive and vascular function in older adults with preclinical cognitive impairment with and without CKD. In our study, 48 older adults underwent assessment of cognition, vascular compliance, and sedentary behavior, and relationships were explored with regression moderation analysis. Sedentary time and breaks did not moderate the relationship between vascular and cognitive function. Although significant moderation was not found, cognition, vascular function, and sedentary behavior are important to assess when evaluating older adults with and without CKD.
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Hannan et al. (2021) conducted a cross-sectional in Preclinical cognitive impairment with and without chronic kidney disease (n=48). Sedentary behavior was evaluated on Moderation of the relationship between vascular and cognitive function. Sedentary time and breaks did not moderate the relationship between vascular and cognitive function in older adults with preclinical cognitive impairment with and without CKD.
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