Environmental stress factors may be responsible for biological changes in living species that are able to overcome deleterious effects depending on their detoxifying capacities. Defense systems present in every living species are involved in elimination of reactive chemical species of endogenous or exogenous origin, neutralization of their effects, repair of initial lesions, and compensation of deficient metabolic pathways. Consequently, the performance of defense systems and their inducibility will explain adaptation to environmental disturbances, whereas their alteration will augur toxicity in the exposed species. Several field studies have illustrated the relationships between antioxidants and toxicity in benthic invertebrates in rivers. They highlighted that defense systems may be useful biomarkers in mechanistic studies of ecotoxicity and in the biomonitoring of living species in polluted environments.
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Vasseur et al. (2004) studied this question.
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