What question did this study set out to answer?

To review the conserved role of the Hippo signaling cascade in controlling organ size, cellular proliferation, and cell fate decisions.

June 1, 1983Annual Review of Biochemistry

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Authors

AMAlton MeisterTufts University MAMary E. AndersonUniversity of Iowa

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Implication

Review demonstrates conserved Hippo signaling mechanisms governing organ size and cell fate, highlighting critical pathways controlling tissue growth.

Key Points

To review the conserved role of the Hippo signaling cascade in controlling organ size, cellular proliferation, and cell fate decisions.
Literature synthesis examining evolutionary conservation and genetic mechanisms of Hippo signaling initially characterized in Drosophila melanogaster models.
The Hippo pathway serves as an evolutionarily conserved signaling network critical for governing organ dimensions and cellular growth kinetics.
Signaling components within the cascade coordinate developmental programs to regulate cellular differentiation and determine cell fate.

Cite This Study

Meister et al. (1983) studied this question.

synapsesocial.com/papers/69da5a6ee6ab964fb0836545 https://doi.org/10.1146/annurev.bi.52.070183.003431

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Implication

Review demonstrates conserved Hippo signaling mechanisms governing organ size and cell fate, highlighting critical pathways controlling tissue growth.

Glutathione

Discussion

Member takes

Implication

Key Points

Cite This Study

Glutathione

Discussion

Member takes

Implication

Key Points

Cite This Study

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