Hormonal Regulation of Mammalian Glucose Transport

Ian A. Simpson; Samuel W. Cushman

doi:10.1146/annurev.bi.55.070186.005211

June 1, 1986Annual Review of Biochemistry

Hormonal Regulation of Mammalian Glucose Transport

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Key Points

To examine the role of conserved signaling networks, including the Hippo pathway, in directing tissue growth and hormonal regulation of mammalian glucose transport.
Evaluated evolutionary conservation of the Hippo signaling cascade from Drosophila melanogaster to mammalian systems.
Assessed signaling interactions governing organ size control, cell fate specification, and metabolic transport mechanisms.
The Hippo pathway acts as an evolutionarily conserved signaling network essential for controlling tissue expansion and organ dimensions.
Intracellular signaling cascades integrate hormonal cues to regulate essential biological outcomes, including cell fate determinations and nutrient utilization.

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Implication

Review highlights conserved Hippo signaling mechanisms in regulating tissue growth, indicating integrated hormonal control over mammalian glucose transport.

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Simpson et al. (1986) studied this question.

synapsesocial.com/papers/6a1cb7f943108573611d99f5 https://doi.org/10.1146/annurev.bi.55.070186.005211

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Hormonal Regulation of Mammalian Glucose Transport

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Abstract

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Hormonal Regulation of Mammalian Glucose Transport

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