Research work of the past few years has suggested the rather anomalous fact that the administration of estrogens (and diethylstilbestrol) in certain amounts may be ~ffeetive in stimulating the initiation of milk secretion in virgin or parous non-lactating animals while at the same time established lactation may be seriously depressed by these same hormones. Folley et al. (4, !Kany investigators (see Meites and Turner ( In goats de Fremery (7) reported depression of lactation with estrogen and in cattle Folley (2) and Walker and Stanley (25) observed similar effects. These latter workers suggested that large, amounts of estrogen inhibit while smaller amounts stimulate milk secretion.
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Mixner et al. (1944) studied this question.
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