Population
In vitro rat carotid body preparation
Comparison
5-min bouts of severe, moderate, or mild… vs Prehypoxic levels (normoxia, 100 Torr Po2)
Design
Preclinical
Authors
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Should not alter clinical hypoxia management; leaves open peripheral afferent contributions to human ventilatory responses in intermittent hypoxia.
Carotid body afferent activity undergoes time-dependent modulation during and after intermittent hypoxia, suggesting a peripheral contribution to ventilatory dynamics.
Cummings et al. (2005) studied this question.
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