Why the study?
Does chronic hypoxia upregulate AT(1) receptor expression and function in the rat carotid body?
Population
Rat carotid body model
Comparison
Chronic hypoxia vs Normoxic controls
Design
Preclinical
Authors
Loading...
May modulate cardiorespiratory responses in hypoxia; hypothesis-generating from rat data only.
Does chronic hypoxia upregulate AT(1) receptor expression and function in the rat carotid body?
Chronic hypoxia upregulates AT(1) receptor expression and enhances its mediated excitation in the rat carotid body, which may play a role in modulating cardiorespiratory functions during chronic hypoxia.
Leung et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: