Why the study?
Does AT1R inhibition reduce androgen receptor expression and cell proliferation in prostate cancer cells?
Does AT1R inhibition reduce androgen receptor expression and cell proliferation in prostate cancer cells?
Inhibition of the angiotensin II type 1 receptor decreases androgen receptor expression and cell proliferation in prostate cancer cells, suggesting a potential novel therapeutic target for prostate cancer.
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AT1R inhibition may offer a novel prostate cancer target; hypothesis-generating and should not change practice.
Hoshino et al. (2010) studied this question.
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