Why the study?
Does a fixed low-dose combination of perindopril/indapamide reduce blood pressure equivalently to atenolol in patients with essential hypertension?
Population
446 patients with essential hypertension, mean age 55.8 +/- 11.0 years.
Comparison
Fixed low-dose combination perindopril 2 mg /… vs Atenolol 50 mg for 12 weeks.
Design
RCT, parallel-group, double-blind
Follow-up
12 weeks
Authors
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Supports perindopril/indapamide as equivalent to atenolol for BP lowering; confirms equivalence in essential hypertension.
Does a fixed low-dose combination of perindopril/indapamide reduce blood pressure equivalently to atenolol in patients with essential hypertension?
A fixed low-dose combination of perindopril and indapamide provides equivalent blood pressure reduction to atenolol in patients with essential hypertension over 12 weeks.
Mallion et al. (2000) studied this question.
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