December 1, 2021European Journal of Hybrid ImagingOpen Access

Combined simultaneous FDG-PET/MRI with T1 and T2 mapping as an imaging biomarker for the diagnosis and prognosis of suspected cardiac sarcoidosis

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Why the study?

The study evaluated F-FDG PET/MRI with T1/T2 mapping in the evaluation of suspected cardiac sarcoidosis.

Does combined simultaneous FDG-PET/MRI with T1 and T2 mapping predict MACE in patients with suspected cardiac sarcoidosis?

Follow-up

Median 634 days

Authors

ECEdward CheungUniversity Health Network SASarah Aftab AhmadSt. Francis Medical Center MAMatthew AitkenGold Coast Hospital

Discussion

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Implication

May aid MACE risk stratification in suspected cardiac sarcoidosis; hypothesis-generating and requires prospective validation.

Structured PICO

Does combined simultaneous FDG-PET/MRI with T1 and T2 mapping predict MACE in patients with suspected cardiac sarcoidosis?

Population

42 patients with suspected cardiac sarcoidosis, mean age 53 ± 13 years, 67% male. 13 (31%) had a final diagnosis of cardiac sarcoidosis.

Intervention

Combined simultaneous F-fluorodeoxyglucose (FDG) PET/MRI with T1 and T2 mapping, including late gadolinium enhancement (LGE) and calculation of extracellular volume (ECV)

Outcome

Major adverse cardiac events (MACE) assessed as a composite of cardiovascular death, ventricular tachyarrhythmia, bradyarrhythmia, cardiac transplantation or heart failurecomposite

Combined FDG-PET/MRI with T1/T2 mapping provides complementary diagnostic information and strongly predicts MACE in patients with suspected cardiac sarcoidosis.

Cite This Study

Cheung et al. (2021) studied this question.

synapsesocial.com/papers/6a86552dd94e0117716392ca https://doi.org/10.1186/s41824-021-00119-w

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Combined simultaneous FDG-PET/MRI with T1 and T2 mapping as an imaging biomarker for the diagnosis and prognosis of suspected cardiac sarcoidosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Combined simultaneous FDG-PET/MRI with T1 and T2 mapping as an imaging biomarker for the diagnosis and prognosis of suspected cardiac sarcoidosis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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