Population
Skeletal muscle (sartorius, rectus abdominis) and heart ventricle preparations
Comparison
Ringer solution made hypertonic by the addition… vs Normal Ringer solution
Design
Preclinical
Follow-up
about 60 minutes
Authors
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Glycerol's unique restorative effect on hypertonic muscle twitch may elucidate excitation-contraction coupling; leaves open translation beyond amphibian models.
Glycerol exerts a peculiar restorative effect on the mechanical twitch response of skeletal muscle in hypertonic solutions, providing insights into excitation-contraction coupling.
Yamaguchi et al. (1962) studied this question.
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