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June 2, 2022Neural Regeneration ResearchOpen Access

The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation

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Authors

XFXinxin FuZhejiang UniversityRDRui DuanHouston MethodistBWBin WeiNanchang University

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Fu et al. (2022) studied this question.

synapsesocial.com/papers/6a86643bf1d53c1caa3a64afhttps://doi.org/10.4103/1673-5374.346468
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microglia in Alzheimer’s disease2017 · 1,998 citations
  2. 2The Role of TREML2 in Alzheimer’s Disease2020 · 18 citations
  3. 3Microglia Polarization in Alzheimer’s Disease: Mechanisms and a Potential Therapeutic Target2021 · 106 citations
  4. 4TREML2 Mutation Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration2019 · 10 citations