Why the study?
Does antiplatelet therapy within 7 days prior to surgery increase bleeding and transfusion rates in patients undergoing coronary artery bypass grafting?
Population
80 patients undergoing coronary artery bypass grafting
Comparison
Aspirin and/or clopidogrel/ticlopidine within 7… vs No antiplatelet therapy for at least 8…
Design
Cohort
Follow-up
Intraoperatively and during stay in the intensive care unit
Authors
Loading...
Antiplatelet use before CABG was associated with more bleeding and transfusions; leaves open optimal perioperative timing pending randomized confirmation.
Does antiplatelet therapy within 7 days prior to surgery increase bleeding and transfusion rates in patients undergoing coronary artery bypass grafting?
Antiplatelet therapy within 7 days prior to CABG significantly increases postoperative bleeding and transfusion requirements, suggesting it should be discontinued for at least 2 days before elective surgery.
Picker et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: