Why the study?
Does recombinant human GH dose correlate with serum levels of IGF-I, IGFBP-3, and ALS in GH-deficient men?
Population
46 GH-deficient (GHD) men
Comparison
Recombinant human GH for 1 year vs Placebo
Design
RCT, double blind
Follow-up
1 year
Authors
Loading...
IGF-I should guide GH titration in young GHD men to avoid excess; confirms its superiority as the preferred marker versus IGFBP-3 and ALS.
Does recombinant human GH dose correlate with serum levels of IGF-I, IGFBP-3, and ALS in GH-deficient men?
Serum IGF-I is the preferred biochemical marker for monitoring GH replacement therapy and detecting GH excess in adults.
Boer et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: