Why the study?
Do high endogenous adiponectin levels improve left ventricular function and reduce cardiac inflammation in patients with inflammatory cardiomyopathy?
Population
173 patients with inflammatory cardiomyopathy, 30 patients with non-inflammatory dilated cardiomyopathy, and…
Comparison
High endogenous adiponectin levels; adiponectin… vs Low endogenous adiponectin levels…
Design
Cohort
Authors
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High adiponectin levels were associated with better LVEF recovery in DCMi; hypothesis-generating for targeted therapies and requires prospective validation.
Do high endogenous adiponectin levels improve left ventricular function and reduce cardiac inflammation in patients with inflammatory cardiomyopathy?
Endogenous adiponectin acts as an anti-inflammatory cytokine that is upregulated in inflammatory cardiomyopathy and is associated with improved left ventricular function and reduced cardiac inflammation.
Bobbert et al. (2011) studied this question.
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