Why the study?
Does propafenone, procainamide, or amiodarone improve the restoration of sinus rhythm within 60 minutes in patients with paroxysmal atrial fibrillation at the prehospital stage?
Does propafenone, procainamide, or amiodarone improve the restoration of sinus rhythm within 60 minutes in patients with paroxysmal atrial fibrillation at the prehospital stage?
Propafenone demonstrated the highest efficacy (73.2%) for rapid (within 60 minutes) prehospital pharmacological cardioversion of paroxysmal atrial fibrillation compared to procainamide and amiodarone.
Hypothesis-generating for agent selection in paroxysmal AF; leaves open need for randomized confirmation before practice change.
This study demonstrates the effectiveness of procainamide, propafenone and amiodaronefor pharmacological cardioversion in patients with paroxysmal atrial fibrillation. The restoration of the sinus rhythm within 60 minutes was observed for propafenone 73,2%, for procainamide 55,00% and for amiodarone 16,13% of cases.
No takes yet. Share an insight, caveat, or question.
Lukianova et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: