Why the study?
Does short-term swim exercise prior to doxorubicin exposure prevent doxorubicin-induced cardiac dysfunction in rats?
Population
69 female albino rats
Comparison
3 days of swim exercise just before a single… vs Sedentary control, doxorubicin alone, and…
Design
Preclinical
Authors
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Short-term pre-doxorubicin exercise may worsen cardiotoxicity in rats; leaves open optimal timing or duration in anthracycline models.
Does short-term swim exercise prior to doxorubicin exposure prevent doxorubicin-induced cardiac dysfunction in rats?
Short-term swim exercise immediately prior to doxorubicin exposure exacerbates cardiac dysfunction and arrhythmia risk in a rat model, despite improving oxidative status.
Diab et al. (2018) studied this question.
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