Why the study?
Does dobutamine infusion alter haemodynamic parameters in patients with coronary artery disease?
Population
12 patients with coronary artery disease
Design
Case_series
Authors
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May guide lower-dose dobutamine titration to prioritize inotropy in CAD; hypothesis-generating and requires randomized confirmation.
Does dobutamine infusion alter haemodynamic parameters in patients with coronary artery disease?
Dobutamine demonstrates a dose-dependent separation of inotropic and chronotropic effects, increasing stroke volume at lower doses and heart rate at higher doses in patients with coronary artery disease.
Magnani et al. (1977) studied this question.
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