Why the study?
Does acute administration of atenolol improve the relationship between heart rate and QT interval during exercise in patients with coronary artery disease?
Population
Control subjects and patients with coronary artery disease with effort angina and without previous…
Comparison
Atenolol 100 mg oral (acute administration) vs Baseline without therapy, and healthy control…
Design
Cohort
Follow-up
Acute
Authors
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May support atenolol to shorten QT at high heart rates in CAD exercise; hypothesis-generating, needs RCT confirmation before practice change.
Does acute administration of atenolol improve the relationship between heart rate and QT interval during exercise in patients with coronary artery disease?
Acute administration of atenolol shortens the QT interval at high heart rates during exercise-induced ischemia in patients with coronary artery disease.
Ferraro et al. (1992) studied this question.
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