January 1, 1974Journal of Supramolecular StructureOpen Access

The contractile proteins of dictyostelium discoideum

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Population

Amoebae of Dictyostelium discoideum

Design

Preclinical

Authors

JSJames A. SpudichHeart Failure & Transplant MCMargaret ClarkeOklahoma Medical Research Foundation

Discussion

Member takes

Implication

Extends actomyosin characterization to Dictyostelium; leaves open relevance to mammalian cardiovascular cell biology.

Structured PICO

Population

Amoebae of Dictyostelium discoideum

Intervention

Purification and biochemical/structural characterization of actin and myosin-like proteins

Outcome

Physical and enzymatic properties, filament formation, and ATPase activity

Actin and myosin-like proteins in Dictyostelium discoideum share similar physical and enzymatic properties with muscle contractile proteins, including filament formation and ATPase activation.

Cite This Study

Spudich et al. (1974) studied this question.

synapsesocial.com/papers/6a86a3b22ccb7b2c5b17addc https://doi.org/10.1002/jss.400020209

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