Why the study?
Does muscle flap denervation improve microcirculatory dynamics in a rat cremaster muscle model?
Population
50 male Sprague-Dawley rats
Comparison
Muscle flap denervation vs Control group with intact neurovascular pedicle
Design
Preclinical
Follow-up
14 days
Authors
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Denervation-linked perfusion gains in rat flaps; hypothesis-generating for clinical microsurgery with no human data yet.
Does muscle flap denervation improve microcirculatory dynamics in a rat cremaster muscle model?
Muscle flap denervation significantly increases capillary perfusion and arteriolar diameter in a rat cremaster muscle model, providing a useful model for chronic in vivo microcirculation studies.
Siemionow et al. (1994) studied this question.
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