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February 26, 2017European Journal of Cardio-Thoracic Surgery

Single coronary artery and neonatal arterial switch operation: early and long-term outcomes†

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Why the study?

Does the presence of a single coronary artery affect early and long-term mortality and coronary events in neonates undergoing arterial switch operation for transposition of the great arteries?

Population

73 neonates with transposition of the great arteries and a single coronary artery, mean age at operation 9.3…

Design

Cohort

Follow-up

mean 9.8 years (range: 1-20 years)

Authors

SGSébastien GerelliMPMargaux PontaillerBRBruno Rochas

Discussion

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Overview

Single coronary artery was not associated with excess late mortality after neonatal ASO; extends prior reports by showing era-dependent risk reduction.

Structured PICO

Does the presence of a single coronary artery affect early and long-term mortality and coronary events in neonates undergoing arterial switch operation for transposition of the great arteries?

P
Population
73 neonates with transposition of the great arteries (TGA) and a single coronary artery (from a total cohort of 979 neonates undergoing ASO), mean age at operation 9.3 ± 5.7 days.
I
Intervention
Arterial switch operation (ASO)
O
Outcome
Mortality and coronary artery stenosis risk at early and long termhard clinical

A single coronary artery is no longer a significant risk factor for early and late mortality after neonatal arterial switch operation for transposition of the great arteries, reflecting improved surgical experience over time.

Cite This Study

Gerelli et al. (2017) studied this question.

synapsesocial.com/papers/6a86ad36a810ea404bcf7b20https://doi.org/10.1093/ejcts/ezx046
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Intramural coronary arteries and outcome of neonatal arterial switch operation2010 · 79 citations
  2. 2Coronary Artery Pattern and Outcome of Arterial Switch Operation for Transposition of the Great Arteries2002 · 357 citations
  3. 3Arterial switch operation: a new technique of coronary transfer1994 · 20 citations
  4. 4Cardiovascular Outcomes After the Arterial Switch Operation for D-Transposition of the Great Arteries2012 · 359 citations
  5. 5Evolution of risk factors influencing early mortality of the arterial switch operation1999 · 152 citations