Why the study?
Does a 6 h continuous infusion of exendin-4 affect regional haemodynamics in conscious rats?
Does a 6 h continuous infusion of exendin-4 affect regional haemodynamics in conscious rats?
Exendin-4 infusion in rats produces complex, regionally selective cardiovascular effects involving both autonomic nervous system-dependent mechanisms and a novel non-autonomic vasoconstrictor action.
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Hypothesis-generating in rats; leaves open whether exendin-4's regional haemodynamic effects translate to humans.
Gardiner et al. (2008) studied this question.
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