What question did this study set out to answer?

Determine whether localized immune hypersensitivity via the Arthus reaction can be induced directly within cardiac and pericardial tissues.

January 1, 1932The Journal of Experimental MedicineOpen Access

The Arthus Phenomenon

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Authors

DSDavid SeegalTulane University BSBeatrice Carrier SeegalColumbia University EJElizabeth L. JostInstitute for Sustainable Development

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Implication

Experimental study demonstrates intense cardiovascular inflammation in sensitized rabbits, indicating localized hypersensitivity reactions within cardiac tissues.

Key Points

Determine whether localized immune hypersensitivity via the Arthus reaction can be induced directly within cardiac and pericardial tissues.
Sensitized rabbits against a specific antigen.
Administered an intrapericardial injection of the homologous antigen.
Regularly induced an intense inflammatory reaction localized to the pericardium, myocardium, and intrapericardial aorta.

Cite This Study

Seegal et al. (1932) studied this question.

synapsesocial.com/papers/6a86b4bce0e6abca40d3b37a https://doi.org/10.1084/jem.55.1.155

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Implication

Experimental study demonstrates intense cardiovascular inflammation in sensitized rabbits, indicating localized hypersensitivity reactions within cardiac tissues.

The Arthus Phenomenon

Discussion

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Implication

Key Points

Cite This Study

The Arthus Phenomenon

Discussion

Member takes

Implication

Key Points

Cite This Study

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