Why the study?
Do systemic hypoxia and hypercapnia cause cutaneous vasodilation in healthy humans?
Population
35 healthy subjects
Comparison
Isocapnic hypoxia, hyperpnea, and hypercapnia… vs Baseline measurements and intra-subject…
Design
Other
Authors
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Hypoxia elicits cutaneous vasodilation independent of adrenergic activity in healthy humans; extends mechanistic insight but leaves open clinical relevance.
Do systemic hypoxia and hypercapnia cause cutaneous vasodilation in healthy humans?
Systemic hypoxia and hypercapnia cause modest vasodilation in nonacral skin, with hypercapnic vasodilation potentially restrained by adrenergic vasoconstriction.
Simmons et al. (2007) studied this question.
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