Key result
Multimodal brain imaging reveals structural and functional brain changes related to lifestyle factors such as obesity and physical activity, suggesting these metrics can serve as surrogate markers for early intervention in cognitive decline.
Population
Individuals with age-related cognitive decline, mild cognitive impairment, and dementia
Design
Review
Authors
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Should not yet change practice for cognitive decline; leaves open utility of imaging biomarkers in prospective lifestyle trials.
Preventive neuroradiology using multimodal brain imaging can help identify the effects of modifiable lifestyle factors like physical activity and obesity on brain aging and cognitive decline.
Raji et al. (2015) conducted a review in Age-related cognitive decline. Lifestyle modifications (obesity and physical activity) was evaluated. Multimodal brain imaging reveals structural and functional brain changes related to lifestyle factors such as obesity and physical activity, suggesting these metrics can serve as surrogate markers for early intervention in cognitive decline.
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