Key result
Intravenous amiodarone infusion induced acute hepatitis within 1 day in a 72-year-old woman with paroxysmal atrial fibrillation, which resolved after stopping the drug.
Why the study?
Does intravenous amiodarone cause acute hepatitis in patients with atrial fibrillation?
Case Report (n=1)
Does intravenous amiodarone cause acute hepatitis in patients with atrial fibrillation?
Intravenous amiodarone can induce acute hepatitis within 1 day of initiation, which is reversible upon discontinuation.
Answers are grounded in this paper and cite their sources.
May warrant LFT monitoring with IV amiodarone in AF; leaves open true incidence.
We report a case of intravenous infusion amiodarone induced acute hepatitis, occurs within 1 day after initiation of drug in a 72-year-old woman with paroxysmal atrial fibrillation. Liver function test before intravenous infusion amiodarone treatment was normal. She was treated with intravenous infusion amiodarone, and then developed acute hepatitis next day. We suspected drug induced hepatitis due to intravenous infusion amiodarone. The liver function test returned to normal after the amiodarone was stopped. We described an unusual case which intravenous infusion amiodarone induced acute hepatitis within.
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Lee et al. (2015) conducted a case report in Paroxysmal atrial fibrillation (n=1). Intravenous infusion amiodarone was evaluated on Acute hepatitis. Intravenous amiodarone infusion induced acute hepatitis within 1 day in a 72-year-old woman with paroxysmal atrial fibrillation, which resolved after stopping the drug.
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