What question did this study set out to answer?

To assess the success rate of direct current cardioversion for chronic atrial fibrillation and evaluate its subsequent hemodynamic impacts using radioisotope dilution.

January 1, 1969Japanese Circulation Journal-english EditionOpen Access

DC Defibrillation of Atrial Fibrillation and its Hemodynamical Effects, studied by Radioisotope Dilution Method

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Why the study?

Does DC cardioversion restore normal sinus rhythm and improve hemodynamics in patients with chronic atrial fibrillation?

Population

32 patients with chronic atrial fibrillation

Comparison

DC cardioversion using a R-synchronized DC… vs Baseline state during arrhythmia

Design

Case_series

Follow-up

2 months to 2 years

Authors

TTTorao TakahashiChukyo Hospital

Discussion

Member takes

Implication

Supports feasibility of DC cardioversion in chronic AF with exertional gains; leaves open confirmation in prospective trials.

Key Points

To assess the success rate of direct current cardioversion for chronic atrial fibrillation and evaluate its subsequent hemodynamic impacts using radioisotope dilution.
Administered R-synchronized direct current cardioversion across 58 separate trials in 32 patients with chronic atrial fibrillation.
Measured hemodynamic changes—including cardiac index, circulating blood volume, and mean pulmonary circulation time—at rest and during exercise using the radioisotope dilution method.
Cardioversion successfully restored sinus rhythm in 85% of trials (49/58) and 91% of patients (29/32), with 59% of patients maintaining sinus rhythm between two months and two years.
Restoration of sinus rhythm produced a significant 24% increase in exertional cardiac index, alongside an 18% reduction in resting and a 16% reduction in exertional mean pulmonary circulation time.
Circulating blood volume expanded by 3% to 4% at rest and 8% during exercise, while exertional stroke volume was preserved relative to resting levels.

Structured PICO

Does DC cardioversion restore normal sinus rhythm and improve hemodynamics in patients with chronic atrial fibrillation?

Population

32 patients with chronic atrial fibrillation

Intervention

DC cardioversion using a R-synchronized DC cardioverter

Comparator

Baseline state during arrhythmia

Outcome

Success rate of cardioversion and maintenance of normal sinus rhythmsurrogate

DC cardioversion is highly effective at restoring sinus rhythm in chronic atrial fibrillation and significantly improves exertional hemodynamics.

Cite This Study

Torao Takahashi (1969) studied this question.

synapsesocial.com/papers/6a86c68ca810ea404bcf84a9 https://doi.org/10.1253/jcj.33.251

Topics

Mitral valve intervention Valvular heart disease Atrial fibrillation Persistent AF management Sermorelin

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DC Defibrillation of Atrial Fibrillation and its Hemodynamical Effects, studied by Radioisotope Dilution Method

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

DC Defibrillation of Atrial Fibrillation and its Hemodynamical Effects, studied by Radioisotope Dilution Method

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider