Key result
Greater cerebrovascular risk factors were associated with poorer executive functioning (b = -0.86; p=0.041) and working memory (b = -0.90; p=0.024) in adults with major depressive disorder.
Cross-Sectional (n=198)
Effect estimate: b = -0.86
p-value: p=0.041
In adults with major depression, cerebrovascular risk factors and subclinical vascular dysfunction are independently associated with worse neuropsychological performance.
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May support vascular screening in MDD with cognitive symptoms; hypothesis-generating for causality and interventions.
Smith et al. (2007) conducted a cross-sectional in Major depressive disorder (n=198). Cerebrovascular risk factors and vascular dysfunction was evaluated on Neuropsychological performance (executive functioning, working memory, and verbal recall) (b = -0.86, p=0.041). Greater cerebrovascular risk factors were associated with poorer executive functioning (b = -0.86; p=0.041) and working memory (b = -0.90; p=0.024) in adults with major depressive disorder.
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