Population
Neurosecretory anterior pituitary GH(4)C(1) cells
Comparison
Membrane depolarization vs Baseline/repolarization state
Design
Preclinical
Authors
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No immediate clinical implications; leaves open whether depolarization downregulates L-type currents in cardiomyocytes.
Membrane depolarization induces a rapid, reversible, and calcium-dependent down-regulation of L-type calcium channel currents in pituitary GH4C1 cells.
Peri et al. (2001) studied this question.
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