Population
Glycerinated psoas fibers
Comparison
Cross-linking with dimethyl suberimidate and… vs Various stages of cross-linking or…
Design
Preclinical
Authors
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Challenges prior myosin head cross-linking reports; hypothesis-generating for thick filament roles in force loss and needs in vivo validation.
Cross-linking of rod segments within the thick filament core abolishes isometric force without affecting myofibrillar ATPase activity, challenging previous reports on myosin head cross-linking.
Ueno et al. (1987) studied this question.
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