Key result
Multidisciplinary PERTs optimize management of severe acute pulmonary embolism in pregnant patients.
Why the study?
Severe acute PE management is challenging in pregnant women, who are excluded from randomized trials, leaving specific guideline recommendations unavailable.
This narrative review highlights the multidisciplinary management of severe acute pulmonary embolism in pregnant women, a population typically excluded from randomized trials.
PERTs may aid complex PE decisions; leaves open outcome impact without prospective validation.
Acute pulmonary embolism (PE) has a heterogeneous clinical presentation, varying from mild chest symptoms to shock or cardiac arrest. Optimal management of severe acute PE requires assessment of multiple parameters to confirm the diagnosis and assess the patient's prognosis, preferably by EXPERT-PE care/Pulmonary Embolism Response Teams (PERTs), integrating multidisciplinary expertise to optimize PE management. While management of severe acute PE already can be challenging, this particularly applies to certain patient subgroups, in particular pregnant women. As a result of ruling out pregnant women in randomized trials, specific guideline recommendations on severe PE are unavailable. This case-based narrative review aims to provide an overall overview of the approach to treating patients with severe PE, based on the comprehensive case description of a pregnant patient with high-risk PE.
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Stenger et al. (2026) conducted a review in Severe acute pulmonary embolism in pregnancy (n=1). Multidisciplinary management (Pulmonary Embolism Response Teams) was evaluated. A multidisciplinary approach using Pulmonary Embolism Response Teams (PERTs) is highlighted for managing severe acute pulmonary embolism in pregnant patients.
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