August 1, 1986Acta Physiologica Scandinavica

On the patterns of blood pressure, heart rate, and blood levels of noradrenaline and adrenaline during haemorrhage in the rat

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Population

Sprague-Dawley rats (awake, unstressed or anaesthetized with different anaesthetics)

Design

Preclinical

Follow-up

4 hours

Authors

JHJan HäggendalUniversity of Gothenburg

Discussion

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Implication

Sympathetic phases in rat haemorrhage extend experimental models; leaves open translation to human hypovolemic shock.

Structured PICO

Population

Sprague-Dawley rats (awake, unstressed or anaesthetized with different anaesthetics)

Intervention

Haemorrhage (bleeding towards complete exsanguination or into a reservoir kept at a constant pressure of 35 mmHg)

Outcome

Patterns of mean arterial blood pressure (MAP), heart rate (HR), and blood levels of noradrenaline (NA) and adrenaline (A)surrogate

Haemorrhage in rats induces a complex, four-phase physiological response characterized by fluctuating sympathetic activity and cardiovascular parameters.

Cite This Study

Jan Häggendal (1986) studied this question.

synapsesocial.com/papers/6a86d20f36c36f97809eb8a0 https://doi.org/10.1111/j.1748-1716.1986.tb07936.x

View Full Paper

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On the patterns of blood pressure, heart rate, and blood levels of noradrenaline and adrenaline during haemorrhage in the rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

On the patterns of blood pressure, heart rate, and blood levels of noradrenaline and adrenaline during haemorrhage in the rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider