Key result
Published studies demonstrate the efficacy and safety of low-molecular-weight heparins for perioperative anticoagulation in patients on chronic warfarin therapy, though more data are needed.
Why the study?
Does low-molecular-weight heparin (LMWH) provide effective and safe perioperative anticoagulation bridge therapy in patients on chronic warfarin therapy?
Population
Patients receiving chronic warfarin therapy requiring perioperative anticoagulation
Comparison
Low-molecular-weight heparin as bridge therapy vs Heparin (unfractionated)
Design
Review
Authors
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LMWH may support perioperative bridging in warfarin patients; leaves open need for randomized confirmation before practice change.
Does low-molecular-weight heparin (LMWH) provide effective and safe perioperative anticoagulation bridge therapy in patients on chronic warfarin therapy?
LMWHs show promise for perioperative bridge therapy in patients on chronic warfarin, though further data are required to fully support their use.
Heuts et al. (2004) conducted a review in Patients receiving chronic warfarin therapy requiring perioperative anticoagulation. Low-molecular-weight heparin (LMWH) was evaluated. Published studies demonstrate the efficacy and safety of low-molecular-weight heparins for perioperative anticoagulation in patients on chronic warfarin therapy, though more data are needed.
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