Answers are grounded in this paper and cite their sources.
The equilibrium solubility of aspirin in supercritical CO 2 has been determined using a dynamic method. Measurements were performed at pressures ranging from (10 to 25) MPa and temperatures from (308.15 to 328.15) K. The effect of a polar cosolvent, acetone, on the solubility of aspirin in supercritical carbon dioxide was also studied. The results show that the addition of acetone produces up to a 5-fold increase in the aspirin solubility. The solubility of aspirin in CO 2 is well described by the Peng−Robinson equation of state and density based correlations over the pressure and temperature ranges studied.
No takes yet. Share an insight, caveat, or question.
Huang et al. (2004) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: