October 1, 1976The Journal of Cell BiologyOpen Access

Paramyosin in invertebrate muscles. II. Content in relation to structure and function.

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Population

Three molluscan muscles and four arthropodan muscles

Design

Preclinical

Authors

RLRhea J. C. LevineAllegheny College MEMyra J. ElfvinState University of New York MDMaynard M. DeweyTufts University

Discussion

Member takes

Implication

Findings in invertebrate models warrant no clinical translation; leaves open whether paramyosin ratios regulate mammalian cardiac tension.

Structured PICO

Population

Three molluscan muscles (Aequipecten striated adductor, Mercenaria opaque adductor, and Mytilus anterior byssus retractor) and four arthropodan muscles (Limulus telson, Homarus slow claw, Balanus scutal depressor, and Lethocerus air tube retractor)

Intervention

Quantitative sodium dodecyl sulfate-polyacrylamide gel electrophoresis to calculate paramyosin:myosin heavy chain molecular ratios

Outcome

Correlation of paramyosin:myosin heavy chain molecular ratios with thick filament dimensions and maximum active tension developmentsurrogate

In invertebrate muscles, the ratio of paramyosin to myosin heavy chain correlates positively with thick filament dimensions and maximum active tension development.

Cite This Study

Levine et al. (1976) studied this question.

synapsesocial.com/papers/6a86da707fdf9298f89eb8b0 https://doi.org/10.1083/jcb.71.1.273

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Implication

Findings in invertebrate models warrant no clinical translation; leaves open whether paramyosin ratios regulate mammalian cardiac tension.

Paramyosin in invertebrate muscles. II. Content in relation to structure and function.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Paramyosin in invertebrate muscles. II. Content in relation to structure and function.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider